| Varieties: | Infectious Disease Prevention Medicine |
|---|---|
| Component: | Chemical Synthetic Drugs |
| Type: | The First Class |
| Pharmacodynamic Influential Factors: | Repeated Medication |
| Storage Method: | Prevent High or LowTemperature |
| Transport Package: | Carton |
| Samples: |
|---|
| Customization: |
|---|
Suppliers with verified business licenses
Audited Supplier OXYGIN 5%
OXYTETRACYCLINE INJECTION 5% W/V
Injectable Solution For Veterinary Use
COMPOSITION:
Each ml contains oxytetracycline 50mg
INDICATIONS:
Treatment of diseases caused by oxytetracycline-susceptible organisms in cattle, sheep and goats.
Please see the enclosed insert leaflet for more details.
DOSAGE AND ADMINISTRATION:
Administer by intramuscular injection. The dose is 10mg/kg body weight (2ml/10kg body weight). Treat for 3-5 days depending on the type and severity of the disease.
Cattle 2ml/10kg
Calves 2ml/10kg
Sheep & Goat 2ml/10kg
Pigs 2ml/10kg
Young Animals 4ml/10kg
WITHDRAWAL PERIOD:
21 days for meat and edible tissues 7 days for milk.
STORAGE:
Store in a cool, dry place under 25 ºC, away from direct sunlight.
PRESENTATION: In a 50ml and100ml glass bottle.
VALIDITY: 2 years.
Contraindications and precautions for the use of oxytetracycline
What is oxytetracycline?
Oxytetracycline is used for calf pullorum, lamb dysentery, piglet yellow scour and pullorum, and chick pullorum caused by large intestine, bacillus or salmonella; cattle failure caused by Pasteurella multocida, swine pneumonia, fowl cholera, etc.; Bovine pneumonia, swine asthma, chicken chronic respiratory disease caused by mycoplasma; locally used for uterine abscess, endometritis, etc.; also used for Taylor's disease, actinomycosis, leptospirosis.
The pharmacological effects of oxytetracycline
It has strong antibacterial effect on gram-positive bacteria and gram-negative bacteria; it is also effective against rickettsia, chlamydia, mycoplasma, spirochetes, actinomycetes and some protozoa. Used for calf pullorum, lamb dysentery, piglet yellow diarrhea and pullorum caused by coliform or Salmonella, chick pullorum; cattle failure caused by Pasteurella multocida, swine pneumonia, fowl cholera, etc.; cattle caused by mycoplasma Pneumonia, swine asthma, chronic respiratory disease in chickens, etc.; locally used for uterine abscess, endometritis, etc.; also used for Taylor's disease, actinomycosis, and leptospirosis.
Indications and uses of oxytetracycline
This product is not completely absorbed by oral administration, inhibits microbial activity in the rumen of ruminants, and is rapidly absorbed by intramuscular injection; after absorption, it is widely distributed in various tissues and body fluids of the body. The barrier is mainly excreted through the kidneys in the prototype, and partly circulated through the liver and intestines, with high concentrations in bile and urine.
Combination contraindications of oxytetracycline
1. Other antibiotics: separately administered in combination.
2. 5% glucose, 0.9% sodium chloride: Oxytetracycline hydrochloride can be compatible with most common intravenous injections, but it is unstable in PH value>6, especially in calcium-containing solutions.
3. Preparations containing ginseng, Bupleurum, licorice, cork, coptis and puerariae: combined use to improve the efficacy of tetracycline drugs and reduce side effects.
4. Acidic foods, beverages and traditional Chinese medicine: combined use to promote the absorption of tetracyclines in the gastrointestinal tract and enhance the antibacterial effect of tetracyclines. However, hawthorn is easy to complex with tetracyclines and reduce absorption, so it is not suitable for combined use.
5. Penicillins: Tetracyclines are fast antibacterial drugs, which interfere with the effect of penicillins on bacteria during the breeding period. Avoid using them together.
6. Erythromycin, rifampicin, isoniazid, diaze pam and other drugs with hepatotoxicity: the combined use of these drugs interferes with the hepato-intestinal circulation of these drugs, affects the efficacy, and enhances liver toxicity, so combined use is not recommended.
7. Bacitracin, polymyxin and other nephrotoxic drugs: combined use of nephrotoxicity increases.
8. Strong diuretics: combined with aggravated nephrotoxicity.
9. Glucose solution: combined use to reduce absorption and reduce curative effect.
10. Muscle relaxants: combined use to aggravate the respiratory depression response.
11. Anticonvulsants: The combined use can significantly reduce the blood concentration of deoxyoxytetracycline, and other tetracyclines will not be affected.
12. Sodium bicarbonate: combined use can reduce the absorption of tetracyclines and reduce the activity.
13. Drugs containing metal ions calcium, magnesium, aluminum, bismuth, iron, etc. (including Chinese herbal medicine): combined with tetracyclines to form insoluble complexes, reduce absorption and reduce curative effect. a. Alum: Combined use to generate poorly soluble complexes and reduce the antibacterial effect of tetracyclines. b. Jiangfan pills (contains alum, atractylodes, tangerine peel, magnolia, licorice, red dates): combined to generate insoluble complexes, reduce the antibacterial effect of tetracyclines. c. Calcined oysters (mainly containing calcium carbonate): combined use to reduce the absorption of tetracyclines and reduce antibacterial activity.
14. Polygonum cuspidatum (contains tannins, flavonoids, emodin, polydatin, etc.): Combined use to generate insoluble complexes and reduce the antibacterial effect of tetracyclines.
15. Huanglian Shangqing Pills (including Coptis chinensis, Gardenia, Scutellaria baicalensis Georgi, Fangfeng, ball training, gypsum, etc.): Combined use to generate insoluble complexes and reduce the antibacterial effect of tetracyclines.
16. Antipyretic pills (including dannanxing, bamboo yellow, blue stone, pig tooth soap, etc.): combined use to generate insoluble complexes and reduce the antibacterial effect of tetracyclines.
17. Shihishan (Sedum thistle, Small thistle, lotus leaf, Platycladus orientalis leaf, madder root, Imperata cylindrica root, Moutan bark, Hawthorn, Rhubarb, palm bark): Charcoal Chinese medicine can adsorb tetracycline, and the combined use will reduce its curative effect.
18. Sha Qi San: The combined use of gastric acid reduces the effect of tetracyclines.
19. Yinqiao detoxification tablets (including honeysuckle, forsythia, mint, nepeta, light tempeh, burdock seeds, platycodon, light bamboo leaves, reed root, licorice): combined use makes the effect of Yinqiao detoxification tablets weakened.
20. Baohe pills (including hawthorn, forsythia, Liuqu, Pinellia, tangerine peel, raspberry, wheat inhibit the activity of Baohe pills, so that its efficacy is weakened or eliminated.
21. Combination reduces the antibacterial effect of tetracycline drugs.
22. Sijiqing (mainly containing flavonoids pericyanine, etc.): the combined use can significantly reduce the combined use of tetracycline antibacterial activity and increase liver toxicity.
23. Milk and dairy products: The combined use can significantly reduce the absorption of tetracycline drugs and affect the efficacy.
24. Alkaline foods (such as crackers, soda, beer, etc.): combined use can reduce the absorption of tetracyclines and reduce the efficacy.
Precautions for oxytetracycline
It is also unstable in water soluble, so it should be prepared for immediate use.
Local irritation: This product is administered by injecting hydrochloric acid saline. The solution is strongly acidic and irritating, not suitable.
Double infection: Oral administration can cause intestinal flora disorder, digestive disorders, enteritis and diarrhea, and form a double infection.
Adult ruminants, equine animals and rabbits are not suitable for oral administration.
This product should be kept away from light and airtight, avoid sunlight, avoid mixing with more chlorine-containing tap water and alkaline solutions, and do not use metal containers to hold the medicine.
Withdrawal period: oral administration, 5 days for cattle and sheep, prohibited during milk production; 5 days for pigs. Injection, 22 days for cattle, prohibited during milk production; 20 days for pigs.
Suppliers with verified business licenses
Audited Supplier 
){kind=link}
){kind=link}